Apocalyptic Hope .......... All chip articles ........ Bio-sensors ...... DNA chips ...... nanotechnology
DRUG Delivery System :
Lab on a chip... Intellect
keywords: MEMS, microsensors, sensors, nanotechnology, medical
devices, drug eluting, chemotherapy agents,
"pharmacy on a smart chip",
Persons: John P. Walters National Drug Control Policy "drug
czar" ; Dr. Richard, Seelig, Dr. Howard, Weintraub, Dr.
Sameer Mahta, Robert Langer
MEMS http://en.wikipedia.org/wiki/MEMS
SENSORS http://en.wikipedia.org/wiki/Sensors
" There
will be, in the next generation or so, a pharmacological method
of making people love their servitude, and producing dictatorship
without tears, so to speak, producing a kind of painless
concentration camp for entire societies, so that people will in
fact have their liberties taken away from them, but will rather
enjoy it, because they will be distracted from any desire to
rebel by propaganda or brainwashing, or brainwashing enhanced by
pharmacological methods. And this seems to be the final
revolution."
Aldous Huxley, Tavistock
Group, California Medical School, 1961
http://www.informationliberation.com/?id=23676
From the Newswire :
DNA Vereflu --April 22, 2009 -- portable database monitored by
TPTB ( the powers that be )
STMicroelectronics and Veredus
Laboratories are also honing in on an answer for
those that are squeamish about the spread of the Avian Flu into
the human populace. Put a lab on a chip. One that can tell the
difference in influenza strains within 2 hours. It
will verify whether or not the strain you are ill with is Influenza
A or B, a drug-resistant strain or a mutated variant including
the Avian Flu or H5N1 strain .
All the lab on a chip needs is a bit of
your DNA....whether through blood,
sputum or swab. Where does all that data go later
on? The lab on a chip is portable, maybe FEMA
can stop by and make sure you're ok during the next flu season.
According to Emaxhealth.com,
"VereFlu will enable healthcare professionals [ Ed: and ???] to effectively
monitor mutations of flu viruses and quickly identify the main
strain of the season," said Dr Rosemary Tan, Chief
Executive Officer of Veredus Laboratories.
http://www.opednews.com/articles/Google-Health--Verichip--by-Greg-Nick-090417-594.html
Smaller verichip for vascular implant of medicine -- March 18,
2009
Buy one; get next chip at reduced rate
..." the vascular port containing the
microchip"
Additionally, Medcomp
will buy scanners from VeriChip for use
by healthcare professionals nationwide in order to identify a
patient’s vascular port for correct medication dosage.
[ ed: Quoting Scott Silverman ] : " Not only
will we be selling a smaller version of our microchip [ed: ID
Verichip ] , but we also expect to offer the VeriMed™
Health Link patient identification service [ ed: the health ID
Verichip ] at a reduced rate to all patients who receive a Medcomp vascular port.”
Timothy Schweikert, President of Medcomp,
http://www.businesswire.com/portal/site/google/?ndmViewId=news_view&newsId=20090318005363&newsLang=en
Brain Receptor- manipulation
'Champix' aka 'Chantix' ( varenicline ; Pfizer ) causes suicidal
thoughts, depression. Linked to suicides -- Feb.
2008
"Pfizer, who make the smoking cessation drug Chantix
(varenicline), have updated the drug's
labelling in the United States to reflect the fact
patients may experience "serious
neuropsychiatric symptoms", including suicidal behaviour.
[ Ed: Labelling isn't near as effective as taking it off the
market altogether, if they really cared ]
Although Pfizer's Patient Information sheet mentions vomiting,
nausea, abnormal dreams, sleep disturbance, and constipation, it
fails to alert smokers to less frequent yet more serious risks
such as kidney failure, suicidal thoughts,
hallucinations, psychotic events, joint pain, muscle
pain, arthritis and suicide.
"I started to feel really grouchy all the time, and would
shout and scream at my family for no good reason, which is
totally out of character."
http://www.newwaysclinic.com/champix_side_effects.html
What is NRT ?
Nicotine Replacement Therapy
Pfizer's Chantix : 55
Suicides
http://www.pharmalot.com/2007/11/chantix-and-suicidal-behavior-the-numbers-please/
Womb on a
chip for IVF --July 26, 2007
To tackle these problems, Fujii's team has
created a "lab on a chip" that is 2 millimetres across
and 0.5 millimetres high, in which up to 20
eggs can be fertilised and then grown until
they are ready for implantation. Endometrial cells, which line
real wombs, are also grown in the device, so that the chemicals
they produce can reach the embryos and help them grow. "We
are providing the embryos with a much more comfortable
environment, mimicking what happens in the body," Fujii
says.
http://www.newscientist.com/article/mg19526146.200-wombonachip-may-boost-ivf-successes.html
Cancer pump dispenses overdose that kills -- May 9, 2007
Denise Melanson of Rainbow Lake was among at
least eight people across North America accidentally killed when
an improperly programmed medical pump gave her a lethal dose of
cancer drugs, an report on the 43-year-old woman’s death
revealed Tuesday
http://www.edmontonsun.com/News/Edmonton/2007/05/08/4164628.html
Verichip Board member now board member of Drug Company -- Jan.
11, 2006
Tommy Thompson , Alfacell
http://www.madison.com/tct/news/index.php?ntid=68387&ntpid=7
Mega-info in Drug-delivery systems ( excellent diagrams ) _-
March 24, 2006
http://www.azonano.com/Details.asp?ArticleID=1538
MicroCHIPS drug delivery system -- March 13, 2006
Ed: the question is : Will it
be used for good, or for evil ???
Will this be applied for mind
control ??
BEDFORD, Mass.--(BUSINESS WIRE)--March 13,
2006--Researchers at MicroCHIPS, Inc., have demonstrated for the
first time that it is possible, using an implanted microchip
device and wireless technology, to actively control the release
of drugs in the body over a prolonged period of time.
"This research is an important step toward development of
novel drug delivery systems in which small devices filled with
potent, therapeutic drugs are used to release medicines into the
body as needed," said John Santini,
PhD, president of MicroCHIPS.
The technology, described in the March 12 online edition
of Nature Biotechnology, is unique in
its use of wireless signaling, its system of reservoirs allowing
precise, efficient delivery of solids, liquids or gels, and its
small size. It is not expected to replace all pills or other
forms of drug delivery. Rather, it will deliver proteins, small
molecules and other drugs that are highly
potent, have limited stability, and must be
delivered in precise doses at specific times.
Santini, along with Massachusetts Institute of Technology
Professors Robert Langer, ScD and Michael
J. Cima, PhD, began work on the concept of so-called "intelligent
drug delivery devices" more than a decade ago.
The current study, which used a microprocessor and a power
source, demonstrates the feasibility of what Santini calls "active"
reservoir control. According to Santini, while one
important use of reservoirs is to contain drugs for release,
reservoirs can also be used to selectively expose
biosensors in order to monitor and provide feedback on conditions
in a patient's body. Biosensors may one day be interactively
paired with drug delivery.
http://home.businesswire.com/portal/site/google/index.jsp?ndmViewId=news_view&newsId=20060313005528&newsLang=en
The research, reported in "Chronic, programmed
polypeptide delivery from an implanted multireservoir
microchip," is scheduled for publication online at www.nature.com/naturebiotechnology
on March 12 and in the April print edition of Nature
Biotechnology.
http://www.pharmalive.com/News/index.cfm?articleid=322151&categoryid=21
MicroChips is also working on another type of reservoir
technology, which Santini terms "passive." Passive
reservoir systems use specially-designed, layered polymers which,
when implanted, regulate drug release over time without
microprocessors or power sources, Santini said
http://www.reed-electronics.com/electronicnews/article/CA6315878.html
Drugs, Mind Control and Nazism
http://educate-yourself.org/mc/
http://www.a1b2c3.com/drugs/lsd09.htm
http://www.mindcontrolforums.com/lsd-mc-cia.htm
http://www.whale.to/b/patton.html
http://www.raven1.net/mind-mk.htm
http://www.totse.com/en/conspiracy/mind_control/
Biotech Dollars ; Designer Drugs .. personalized just for you --
Oct. 20, 2005
Ed : Does he mean
subdermal ?
"The right medicine to the right person
at the right dosage at the right time," Tommy
Thompson, former U.S. Health and Human Services
secretary, said Tuesday at what organizers say was the first-ever
business conference on the industry.
Now, more investors and companies are clamoring for
similar profit in personalized medicine. They're
pursuing start-ups that are leveraging advances in
genetics [ Ed : DNA
] to find medicine's holy grail:
drugs that are safer, cheaper and more effective because they're
fine-tuned — or "personalized" — for specific
groups of patients [
Ed : is that the same as "targeting " ? ]
http://www.usatoday.com/tech/news/biotech/2005-10-19-biotech-drugs_x.htm?csp=14
Polymers are plastics ................. and they are everywhere
http://www.efunda.com/materials/polymers/science/polymer_science_intro.cfm
Drug-eluting stents ...polymers -- Aug. 15, 2005
http://www.designnews.com/article/CA632570.html
ChipRx
http://www.technologyreview.com/articles/01/01/innovation70101.asp
Morphine on a chip, remote controlled --Aug 8, 2005
a novel solution - a device implanted into his body which gives
off minute amounts of morphine throughout the day
He is the first person to be implanted with the SynchroMed
device for chronic pain at Tan Tock Seng Hospital
(TTSH). Three other patients who were implanted with this device
were operated on for cancer pain.
It has a computer chip which is controlled by remote
control to deliver medication throughout the day
According to Dr Lee, with all opioids (the major
class of analgesics used in the management of moderate to severe
pain) there's a question of addiction.
http://newpaper.asia1.com.sg/news/story/0,4136,92549,00.html
Pain medication pump systems
http://www.medtronic.com/neuro/paintherapies/pain_treatment_ladder/drug_infusion/pumps_pump_sel/drug_pumps_prog_pumps.html
Former Sen. Bill
Bradley, Director for LabNow ( Lab-on-a-chip) -- Aug. 8, 2005
Rick Hawkins, Chairman and CEO of LabNow,
expressed his excitement regarding Senator Bill Bradley's
appointment. "Senator Bradley brings a wealth of knowledge
and skills to LabNow. HIV/AIDS is a highly politicized disease
and his legislative experience on healthcare issues acquired
during his eighteen years as Senator of New Jersey, the heart of
the pharmaceutical and biotechnology world, is a major asset to
the company. Bill Bradley's accomplishments speak for
themselves...Rhodes Scholar, NBA Hall of Fame, U.S. Senator. I
know that his input will add immeasurable energy and value to
LabNow's cause."
http://home.businesswire.com/portal/site/google/index.jsp?ndmViewId=news_view&newsId=20050808005258&newsLang=en
LabNow licensed lab-on-a-chip sensor technology
from the University of Texas that automates fluid analysis. It
holds promise for HIV/AIDS management as well as other medical
uses, homeland security, environmental chemistry
and process engineering
http://austin.bizjournals.com/austin/stories/2005/08/08/daily6.html
Robert Langer: The Edison of Medicine -- June 12, 2005
Prof. Robert Langer, who has excelled in developing slow-release
technologies for drugs and building platforms for
cells to eventually create new organs
Langer is the man behind the drug-eluting
Cypher stent, a tiny mesh cylinder implanted in
weakened cardiac arteries that slowly releases
chemicals to reduce the risk of restenosis
(re-clogging). This advanced and expensive type of stent was
recently included in Israel's basket of health services. He and
his team also developed coin-sized wafers that slowly
release chemotherapy agents to prevent a malignancy
from returning to the site from which brain tumors have been
removed.
He has also pioneered ultrasound,
magnetic, electrical and enzymatic systems that release drugs in
minute amounts and at a steady rate.
Langer found that an oscillating magnetic field
could "squeeze out" more drug through the pores in a
polymer and be used to deliver 1,000 0.5 mg doses.
On this basis, he and colleagues recently developed a prototype
for a
"pharmacy on a smart chip"
– a dime-sized microchip with 34 drug wells on one side,
each covered by a thin layer of gold – that can be implanted
in a body to monitor blood chemistry and release medication at
specific doses and times as needed.
when a tiny electrical current is applied, the gold dissolves in
a few seconds, allowing the small amount of drug in a particular
well to be released. The device has been designed so that each
well can be opened individually. Thus different drugs or doses
can be contained in different wells and released at different
times.
http://www.jpost.com/servlet/Satellite?pagename=JPost/JPArticle/ShowFull&cid=1118543081042
Drug- dispensing chip -- June 6, 2005
Provides communication between doctors and
devices
A wireless chip has been developed for medical
implants that could allow doctors to monitor a patient's health
from miles away and even control the
release of drugs such as insulin.
.... fitted with such devices as pacemakers and
even brain stimulators.
Doctors will be able to use the chip to do such
things as adjust pacemakers and, eventually, such drug dispensing
devices as implanted insulin pumps.
http://www.betterhumans.com/News/News/tabid/61/News/713/Default.aspx
Pharmaceuticals, EPC and rfid -- April 28, 2005
In the pharma sector an action group has been
formed by EPCglobal Inc called Healthcare Life Sciences Business
Action Group (HLS BAG) comprising leading manufacturers
Essentially, the EPC is a number designed to uniquely identify a
specific item in the supply chain. The EPC number sits on a tag
comprised of a silicon chip and an antenna, which is attached to
an item. Using radio identification technology (RFID), a tag
“communicates” its number to a reader. EPC tags would
carry 96-bit or 128-bit “license plates” that would
identify a manufacturer, describe the product and include a
unique serial number.
Legitimate drug manufacturers overseas would tag their products
and customs agencies and distribution companies would be able to
scan the tags and check a database to verify the origin of the
shipment.
http://www.expresspharmapulse.com/20050428/pharmatechnology09.shtml
Transistors on a sensor-chip -- April 2005
Some companies are already creating products for
this niche. Sensant has created a tiny drum-on-a-chip for
improving ultrasounds, while Pria Diagnostics is testing a chip
for male fertility testing. Meanwhile, Intel, General Electric
and others have developed prototype chips for testing blood
samples.
http://management.silicon.com/itdirector/0,39024673,39129534,00.htm
"Chip of Life" microsensor ( microanalyser
) developed by Sphere -- March 22, 2005
Sphere Medical in Cambridge has fused nano and
microtechnologies to develop a tiny diagnostic chip that will
give doctors access to a range of life-or-death information about
critically ill patients in real-time.
The microanalyser will give immediate access to data which
currently requires a lab test – taking minutes or hours
– or for which there is no test available at the moment.
Sphere’s technology platform is based around a tiny
microchip, a few milimetres square, onto which are fabricated up
to 10 tiny sensors.
http://www.businessweekly.co.uk/news/view_article.asp?article_id=9272
Pharmacy on a chip; polymer discs dissolving-- March 2005
Giant leap forward in bionic medicine
http://www2.rnw.nl/rnw/en/features/science/050228rf
Food and Drug Administration
approved Applied's VeriChip device, an implantable chip
that can be read by a remote sensor to check human vital signs
and diagnose other problems.
http://www.businessweek.com/ap/financialnews/D88N22Q80.htm?campaign_id=apn_tech_down
Will
the elderly and handicapped need the chip for medical services ?
Will this involve a drug delivery system ?
Applied Digital appoints Medical Advisory Board---- Feb. 16, 2005
Drs. Richard Seelig, Howard Weintraub, Sameer Mehta
VeriChip Corporation, has formed a Medical
Advisory Board to assist in expanding the adoption of
VeriChip in the medical community. The Board's initial
focus will be to advise the Company on ways to increase the
acceptance and expand the marketing of VeriChip to practitioners,
hospitals and makers of medical devices, insurance companies and
Medicaid/Medicare
Dr. [Howard] Weintraub is a
principal of the Landfall Therapeutics Consulting Group, LLC,
which provides strategic and technical consulting in the pharmaceutical
and medical device arena. He has more than thirty years of
experience in pharmaceutical and medical device research and
development. Until his retirement in July of 2003, Dr. Weintraub
was Vice President, R&D Corporate Staff for C.R. Bard, the
medical device company. In this role he worked to establish and
maximize synergies across the company's eight development groups,
and was responsible for identification and evaluation of new
technologies.
Previously, Dr. Weintraub held various research management
positions at Ortho Pharmaceutical Corporation, a Johnson &
Johnson Company, where he started and built the drug
metabolism and clinical pharmacology organizations.
In addition he led various project teams including the group that
developed the antidiarrheal, Imodium®. Prior to joining Ortho
Pharmaceutical, he was responsible for dermatological and wound
care research at Bristol-Myers Squibb in the ConvaTec division
and licensed and developed Dovonex(TM), the topical
antipsorriatic product. Dr. Weintraub received his B.S. in
Pharmacy from Columbia University, and his Ph.D. in
biopharmaceutics from the State University of New York at
Buffalo.
Drug Metabolism sub-section, where he helped draft the current bioequivalence/bioavailability
regulations.
He is a member of the Board of Directors of
Digital Angel Corporation (AMEX, DOC), and the privately held
biotechnology company, Bioenergy, Inc. He is
also a member of the scientific advisory board of Polymerix
Corporation, the Strategic Advisory Board of Aderans, Inc., and
the advisory board of the Department of Biomedical Engineering,
Rutgers University.
Dr. [Sameer] Mehta is an experienced
interventional cardiologist and served as Chief of Interventional
Cardiology and Director of the Cardiovascular Library at Cedars
Medical Center in Miami.He has served or currently serves on
numerous Medical and Scientific Advisory and Board of Directors
including EGT Inc, Vizcaya Museum & Gardens, Scimed Inc.,
Spectranetics Inc., Advanced Interventional Systems Inc.
http://biz.yahoo.com/bw/050216/165505_1.html
http://www.tmcnet.com/usubmit/2005/Feb/1118677.htm
Subdermal meds and
illness ID
... drug-delivery systems
Mind
control ? Behavior modification ??
Internal....Drugs-on-a-chip Jan. 28, 2005
Sastry had earlier said this cheaper alternative
to DNA sequencing can be used to treat India-specific genetic
disorders such as hypertension (
Ed: high blood pressure ) and thalassaemia.
While DST has given a grant of Rs one crore for the project,
Sastry had said that the DNA chip,
being developed at the laboratory, will be planted
into the human body to treat ailments. The process
is not only aimed to reduce cost of drug production
and enhance level of automation, but also revolutionize medical
science.
NCL is not only institution attempting to develop a chip. The
Massachusetts Institute of Technology (MIT) is also working on a
chip, which when implanted into the human body with a cocktail of drugs,
can avert any medical emergencies.
On the other hand, a disposable lab-on-a-chip
(inch by inch with 2-3 millimetres thickness) developed by Indian
scientists at the US is also showing promise for conducting
various pathological tests at non-laboratory conditions.
Currently undergoing pre-clinical trials at the US for a couple
of infectious diseases and gynaecological disorders, Handylab,
the spinout company of the university of Michigan, is planning to
tailor-make the chip for detection of diseases at Indian
conditions.
http://www1.timesofindia.indiatimes.com/articleshow/1003957.cms
"Lab-on-a-chip
dispensing drugs
Digital Angel seeks to combine biosensor
with Verichip -- July 2003
"Biosensors are already thriving in the medical field.
External biosensors are used in emergency rooms as point-of-care
diagnostic units—such as i-Stat's "lab on a
chip," which can reveal almost immediately whether
a patient is in cardiac arrest by testing blood chemistry.
Other companies are developing implantable biosensors
that track blood glucose levels and deliver insulin. MicroChips
is testing a chip implant that offers long-term,
time-controlled drug delivery. Digital Angel has
discussed merging its external biosensors with the VeriChip, an
implantable microprocessor.
Other companies are developing implantable biosensors that track
blood glucose levels and deliver insulin. MicroChips is testing a
chip implant that offers long-term, time-controlled drug
delivery. Digital Angel has discussed merging its
external biosensors with the
VeriChip, an implantable microprocessor"
[ Ed: have
NOT seen documented that the internal VeriChip is a
microprocessor ]
http://www.pcmag.com/article2/0,1759,1131605,00.asp
Lifesavers in
their Arms -- Jan. 5, 2005 ..."The VeriChip
System"
Now, patients can have a computer chip embedded
in an arm to provide an electronic link
to their medical information when they can't
communicate or don't have someone to speak for them.
Diabetics may be among the first New Jerseyans offered the choice
of having subcutaneous chips implanted to give
health-care workers access to their medical records.
VeriChip, developed by a retired New Jersey surgeon, was
recently approved by the federal Food and Drug Administration.
The implant is strictly voluntary and requires physician
authorization.
http://www.northjersey.com/page.php?qstr=eXJpcnk3ZjczN2Y3dnFlZUVFeXk2MTAmZmdiZWw3Zjd2cWVlRUV5eTY2MzM0OTkmeXJpcnk3ZjcxN2
Y3dnFlZUVFeXk1
ZipQuill drug delivery system ( no injector)
for vaccines, antibiotics and other pharmaceuticals
http://www.trovan.com/productszip.htm
Coming
: Drug-chips ??? ... "soma, soma, soma "........ May
20-2002
The device has been developed by Massachusetts-based
company MicroCHIPS and has been successfully
tested in a lab rat.
It has been in development for three years and inventor
John Santini is promising it will be ready for humans
within five years.
The fingernail-sized titanium chip is inserted beneath
the skin. It contains hundreds of tiny reservoirs, filled with
different drugs which are released as needed by software on
board.
http://www.ananova.com/business/story/sm_591643.html
and
http://www.micralyne.com/news/microchips03.htm
Israelis develop DNA
Computer --April 28, 2004 ...molecular
computer
"It is decades off, but future
generations of DNA computers could function as doctors inside
cells," researcher Ehud Shapiro of Israel's Weizmann
Institute of Science told Nature.
Dr. Mauro Ferrari, a specialist
in nanotechnology (building products atom by atom) at
the National Cancer Institute, said of the research: "The
concept is to build something that does not require intervention
by a doctor. ... This is very exciting. ... It could allow the
killing of cancer at a very, very early stage."
Advocates say the biocomputers could do the work of physicians by
diagnosing disease within cells as well
as dispensing drugs as required.
Instead of being controlled by silicon chips and electrical
circuits, the molecular, or so-called DNA computer, harnesses DNA
strands to store information. The researchers stress that DNA can
store a huge amount of information.
They point out that the computer power of
1 trillion compact discs could be stored in less than
an ounce of dried DNA. Because billions of the
computers can be packed into a single drop of water, they could
fit easily inside a human cell, Mr. Shapiro said.
When the computer detects abnormal RNA, it releases an
anticancer drug, also made of DNA, which interfere
with a cancer cell's activities, causing it to
self-destruct.
http://www.washingtontimes.com/functions/print.php?StoryID=20040428-105738-9804r
Nanometer chips under
the skin -- Jan. 26, 2005
National Taiwan University released its
groundbreaking study on "Advanced Wireless
Medical Monitoring Systems" on Tuesday,
reporting on the use of nanometer sized chips which are
attached to or inserted under the skin of a person's body and
equipped with nanometer electronic technology permitting monitoring
of the subject's respiration, heartbeat, blood parameters and the
like. At the same time, the data can be transmitted
via a wireless network so that the patient's
data can be sent to a remote handset and computer platform.
The project integrates wireless networks
and computerized artificial intelligence methods to integrate
medical monitoring and diagnosis systems functions
it means that even while sitting comfortably at
home, a doctor can arrive at a diagnosis from a remote hospital
location and provide appropriate care for the patient at home.
SENSORS
sensors, allowing, for example,
monitoring of important indicators like protein hardness,
coagulation, flexibility and density in cardiac patients. The
chips are capable of reading these biophysical signs and
nanometer chips can even be used to directly perform
tests, do analyses, and transmit the results.
http://english.www.gov.tw/index.jsp?id=13&recid=103217&viewdate=0
Nanotechnology; embedded systems
ESPS
Motorola
the development of nanoscale sensors for chem/bio (C/B)
detection in the ESPS Center of Excellence
http://nanotechwire.com/news.asp?nid=1412
ePrescribing :BluefishRx and EpocratesRx (biometric signature)
BluefishRx is an eprescribing application for
Palm handhelds that streamlines the prescription writing process.
With BluefishRx, physicians can manage patient details and drug
history, choose from a database of over 2,500 drugs, and
write prescriptions directly on their handheld in seconds
with a few strokes of the stylus. BluefishRx is now
fully integrated with EpocratesRx. Look up drug dosing ,
formularies, check for drug interactions and more, all while you
write prescriptions.
http://bluefishwireless.com/products/sample_applications.htm
June 6--8 2005 Trax Summit Pharmaceuticals http://www.traxsummit.com
Dr. John Santini -- MicroCHIPS
A PhD graduate of MIT,
Dr. Santini is one of the founding members of MicroCHIPS,
a developer of implantable microchip drug
delivery systems to be used in pain management, hormone
and steroid delivery, and some cancer and CNS disorder therapies. The company's
patented technology uses silicon microchips and wireless
communication to accurately dispense medicine to the body.
http://www.biospace.com/news_story.cfm?StoryID=8802119&full=1
SARS chip in Singapore --Oct. 6, 2003
Singapore
hopes to launch in January [2004] an electronic
chip that will give an almost instant diagnosis of
whether a person has Sars, dengue fever, flu or some other
respiratory illness.
Ren Ee Chee of the government-run Genome Institute of Singapore told the island republic's Sunday Times newspaper that the respiratory pathogens detection chip would undergo testing soon in conjunction with an unnamed US company.
Detection
probes on the chip, which is about the size of a 10p coin, will
analyse saliva or nasal mucus dropped on to it and deliver a
rapid diagnosis.
It is also hoping to turn Singapore into a
global biomedical hub as part of its strategy to
diversify an economy battered by the technology slump.
High-profile scientists including Ian Wilmut, who cloned Dolly
the sheep, have been lured to the tightly controlled state.
http://www.guardian.co.uk/sars/story/0,13036,1056738,00.html
BioMEMS
Micralyne, a developer and OEM and manufacturer of BioMEMS
and other MEMS components, will work with MicroCHIPS as
MicroCHIPS continues device development and proceeds towards
clinical trials.
"We believe that the technology that MicroCHIPS is
developing for implantable MEMS-based drug delivery has the
potential to be an important step forward for the effective
implementation of therapeutic regimens in the future",
commented Chris Lumb, President and CEO of Micralyne. "We
are excited to be involved in this work with MicroCHIPS, and
pleased to be working for the first time in drug delivery, a
relatively new area for BioMEMS applications
http://www.biospace.com/news_story.cfm?StoryID=9846620&full=1
Microchip
releases chemicals on demand
The researchers have demonstrated this for multiple
chemicals in separate reservoirs. In other words, they applied a
small voltage between a reservoir containing chemical A and a
cathode and observed that chemical's release, then at a later
time did the same for a reservoir containing chemical B with the
same results. They did this for several different reservoirs
filled with one or the other chemical over a period of several
hours. This shows "that multiple compounds can be released
independently from a single microchip device," the trio
write in Nature.
http://web.mit.edu/newsoffice/nr/1999/microchip.html
Bush plans mental illness screening for all 'consumers'; even
pre-school --June 19, 2004
Ed. note: Everybody on
a pill ?
A sweeping mental health initiative will be unveiled by President
George W Bush in
July. The plan
promises to integrate mentally ill
patients fully into the community by providing "services
in the community, rather than institutions,"
according to a March 2004 progress report entitled New Freedom Initiative (www.whitehouse.gov/infocus/newfreedom/toc-2004.html). While some praise the plan's
goals, others say it
protects the profits
of drug companies at the expense of the public.
Bush established the New
Freedom Commission on Mental Health in
April 2002 to conduct a "comprehensive study of the United
States mental health service delivery system." The
commission issued its recommendations in July 2003.
Bush instructed more than
25 federal agencies to develop an implementation plan based
on those recommendations.
The commission also recommended "Linkage [of screening] with
treatment and supports" including
"state-of-the-art treatments" using "specific
medications for specific conditions." The
commission commended the Texas Medication Algorithm Project (TMAP)
as a "model" medication treatment plan that "illustrates an evidence-based
practice that results in better consumer outcomes."
Dr Darrel Regier, director of research at the American
Psychiatric Association
(APA), lauded the president's initiative and the Texas
project model saying, "What's nice about TMAP is that this
is a logical plan based on efficacy data from clinical trials."
http://bmj.bmjjournals.com/cgi/content/full/328/7454/1458
http://www.whitehouse.gov/infocus/newfreedom/toc-2004.html
http://psychrights.org/Drugs/AllenJonesTMAPJanuary20.pdf
"Political paranoia" now termed "mental
illness" -- Jan. 10, 2005
Practice First Amendment ( right of dissent ) and be forced to
take drugs
When the 109th Congress
convenes in Washington in January, Senator
Bill Frist, the first
practicing physician elected to the Senate since 1928, plans to
file a bill that would define 'political paranoia' as a mental
disorder, paving the way for individuals who suffer from paranoid
delusions regarding voter fraud, political persecution and FBI
surveillance to receive Medicare reimbursement for any
psychiatric treatment they receive," writes Hermione
Slatkin, Medical Correspondent for the Swift Report. "Rick
Smith, a spokesman for Senator Frist, says
that the measure has a good chance of passing; something that can
only help a portion of the population that is suffering
significant distress."
No need for FEMA camps or
"preventive detention" when we have a "medical
armamentarium" of serotonin
uptake inhibitors. All
that is needed now is for Frist and the Republicans to devise a
law defining "political paranoia" and determining that
"political paranoiacs" are a threat to society.
You will take your Paxil (or something far
more debilitating ) and by court order. Recall Bush's effort to screen the entire
population for mental illness, i.e., the New
Freedom Initiative. Bush's commission found
that "despite their prevalence, mental disorders often go
undiagnosed" and recommended comprehensive mental health
screening for "consumers of
all ages." Naturally, Frist and the Republicans are mostly
concerned about the "political paranoia" form of mental
illness, as the above news item indicates. http://www.rense.com/general61/emen.htm
Compulsory mental health screening coming
There is a new major
U.S. mental health initiative on the docket, based on a report of
the New Freedom in Mental Health Commission, which recommends
mental health screening for adults and children as young as
preschool age, in primary care health settings, schools, and
correctional facilities. It also includes expanding school-based
mental health programs requiring specific treatments for specific
conditions, including the use of specific medications.
Despite a growing public
opposition to universal mental health screening, states are being
encouraged by the federal government to adopt the measure. Last
month Illinois bureaucrats began pushing through a plan passed
into law by their legislature to screen the mental health of all
pregnant women and children up to 18 years of age in their state.
The plan also includes discounted psychotropic drugs.
http://www.raidersnewsupdate.com/hughes.htm
Implantable chip's medical dangers
http://worldnetdaily.com/news/article.asp?ARTICLE_ID=41000
Implantable Medical Devices -- Jan. 20, 2005
medical radio frequency band: MICS Medical Implant Communications
Service
....subcutaneous radios and imaging
Boston -- Cambridge Consultants has designed an intelligent
radio transceiver architecture that introduces a new
level of power economy and performance for in-body
medical diagnostic and therapeutic applications.
The design is intended for implementation on system-on-chip
(SoC) solutions and provides a
control and communications platform
suitable for implantable medical devices
- a market currently growing at double-digit rates. The
device will operate in the Medical Implant Communications Service
(MICS) frequencies - the medical band now emerging as a global
standard.
http://boston.dbusinessnews.com/shownews.php?newsid=8481&type_news=latest
Ardesta DNA lab on a chip http://www.ardesta.com/1network/netcom1.asp
Novartis -- world's largest generic drug manufacturer
-- Feb. 21, 2005
The Swiss drugs
firm Novartis today agreed to buy German firm Hexal and most of
US company Eon Labs in deals worth €5.6bn (£3.8bn). The
acquisitions will make it the world's largest generic drugs
manufacturer.
Daniel Vasella, the Novartis chairman and chief executive, has
long coveted the top spot in the global generics market. The firm
acquired Lek, of Slovenia, in 2002, and bought Sabex, of Canada,
last year
Basel-based Norvatis said it would have had combined generic
sales of around $5.1bn in 2004 if the takeover deals had been in
place then. The figure compared with $4.8bn for the
current world leader, Israel's Teva Pharmaceuticals
http://www.guardian.co.uk/business/story/0,3604,1419267,00.html
Novartis has headquarters in
Boston ( 2002 ) and works with 800 scientists at Cambridge, MA.
Novartis : More innovative
drugs ( chain of genes ) ; less probation time -- July
8, 2005 "new science"
Editor : more risks;
less guarantees ; risking a wrong application
"It's a change in focus," Vasella said in an
interview. "In the optimum case it will take out one year or
two years" from a drug's development time
Driving Novartis's new focus are recent advances in
genetics, which have allowed scientists to better understand the
molecular similarities, or "pathways," between
different diseases. Traditionally, pharmaceutical companies
have tested drugs by targeting a single gene or protein.
What Novartis wants to do, Vasella said, is understand how a chain of genes may be
at the root of several diseases.
If you know that there's a common pathway between two
diseases, then of course the chance that a medicine works in both
is very, very high," he said
The drug development strategy is the brainchild of Mark
Fishman, a former Harvard professor whom Novartis hired in 2002
as its head of global research
Editor : Not clear here:
are they skipping Phase 1 ???
Early stage drug testing, known as Phase 1, is normally
done in healthy volunteers to check whether a drug is safe. Only
later is the drug tested on people with the disease. By
using ill patients, such as with Muckle-Wells sufferers, Novartis
hopes to find out more quickly whether a drug works, and save
money by terminating studies if results are negative.
Another colon cancer drug, known as PTK/ZK, which Novartis is
developing jointly with a German company, Schering,
suffered a setback this year when trials failed to reach
statistical significance
Editor: Only 50
% ....... ?????
Trials are ongoing and the drug has a "50 percent
chance" of making it to the market, Vasella said
http://www.iht.com/articles/2005/07/07/business/novartis.php
Articles:
US shows its muscle in the pharmaceutical industry --
March 5, 2005
http://www.channelnewsasia.com/stories/afp_world_business/view/135818/1/.html
Salvation www.cybertime.net/~ajgood/sal.htm
Bible www.blueletterbible.org